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Image Search Results
Journal: Frontiers in Veterinary Science
Article Title: Detection of bimodal survivin expressions in canine cancer types by flow cytometry compared to immunohistochemistry
doi: 10.3389/fvets.2025.1552415
Figure Lengend Snippet: Analysis of survivin expression sites by IHC and WB. (A) Images of HE staining and survivin expression via IHC in canine melanoma cell lines (CMM2, CMeC, and LMeC) are shown. (B) Images of HE staining and survivin expression via IHC in murine cell lines (p815, CT26, and B16F10) are shown. (C) The cytosol and total survivin expression patterns via WB are indicated. (D) The expression levels of total survivin (blue bar) and cytosolic survivin (orange bar) corrected on the basis of β-actin expression are shown via density of plot analysis via ImageJ software.
Article Snippet: A total of six cell lines were used: canine malignant melanoma lines [CMM2, CMeC2, LMeC; provided by Dr. Takayuki Nakagawa, Department of Veterinary Surgery, University of Tokyo; ( )], the murine malignant melanoma line B16F10, the murine mast cell tumor line p815, and the
Techniques: Expressing, Staining, Software
Journal: Oncology Letters
Article Title: In vivo and in vitro induction of the apoptotic effects of oxysophoridine on colorectal cancer cells via the Bcl-2/Bax/caspase-3 signaling pathway
doi: 10.3892/ol.2017.7227
Figure Lengend Snippet: OSR inhibited the colorectal tumor growth in vivo . (A) Growth curve (the tumor volume) showed that OSR could inhibit the mouse CT26 transplantable colorectal tumor tissue volume significant; (B) OSR inhibited the tumor weight (the 13th day). *P<0.05, **P<0.01 vs. the control group. OSR, oxysophoridine; 5-Fu, fluorouracil.
Article Snippet: Colorectal cancer HCT116 and
Techniques: In Vivo, Control
Journal: Oncology Letters
Article Title: In vivo and in vitro induction of the apoptotic effects of oxysophoridine on colorectal cancer cells via the Bcl-2/Bax/caspase-3 signaling pathway
doi: 10.3892/ol.2017.7227
Figure Lengend Snippet: OSR upregulates the levels of caspase-3, Bax and cytochrome c expression, and downregulates the levels of Bcl-2 and PARP-1 expression in the transplanted mouse CT26 colorectal cancer tissues. (A and B) The levels of caspase-3, Bax, cytochrome c, Bcl-2 and PARP-1 mRNA expression in the transplanted mouse CT26 colorectal cancer tissues. (C and D) The levels of caspase-3, Bax, cytochrome c, Bcl-2 and PARP-1 protein in transplanted mouse CT26 colorectal cancer tissues.*P<0.05, **P<0.01 vs. the control group. OSR, oxysophoridine; Bcl-2, B-cell lymphoma 2; Bax, Bcl-2 associated X protein; PARP-1, poly (adenosine 5′-diphosphate-ribose) polymerase 1.
Article Snippet: Colorectal cancer HCT116 and
Techniques: Expressing, Control